Medical Research Council - London Institute of Medical Sciences

Now in our 8th year of bringing you beautiful imagery from biomedical science every day

Inside View
27 July 2013

Inside View

Subtle changes in tissue that is diseased – with for example early-stage cancer – can be detected by Raman spectroscopy, which analyses patterns of light scattered by the surface of an object, such as a human organ. A Raman device has been made small enough to fit onto an endoscope, a thin tube that is inserted into a patient for internal examination. Pictured, left, is the device attached to the tip of an endoscope and, right, being used to analyse the structure of the wall of the large intestine, or colon, from the scatter pattern of light shone from the endoscope. The scientists who developed the device say that greater sensitivity can be achieved if tissue is laced with glass-coated gold nanoparticles to enhance the scattering of light. They are now seeking regulatory approval to do this in patients.

Written by Mick Warwicker

Search The Archive

Submit An Image

What is BPoD?

BPoD stands for Biomedical Picture of the Day. Managed by the MRC London Institute of Medical Sciences the website aims to engage everyone, young and old, in the wonders of biomedicine. Images are kindly provided for inclusion on this website through the generosity of scientists across the globe.

Read More

BPoD is also available in Catalan at with translations by the University of Valencia.