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Echo the Gecko
04 December 2017

Echo the Gecko

Human spinal injuries often cause permanent paralysis. A severed spinal cord heals over quickly with scar tissue, sealing wounds but also blocking repair to nervous connections. Neuroscientists are now looking at the interesting tail of the leopard gecko for inspiration. Caught by a predator, the spotty lizard simply detaches its flesh and runs off, leaving the severed appendage behind, wriggling as a distraction. Within a month, the gecko grows a completely new tail, with a fresh spinal cord running down inside – all thanks to a special type of stem cell, called a radial glia cell which sets to work after injury. Humans have lots of these cells during development, but they disappear in later life. It’s possible that carefully introducing these cells in adults may prevent scar tissue from forming after injury, and give the spinal cord more chance to heal.

Written by John Ankers

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BPoD stands for Biomedical Picture of the Day. Managed by the MRC Laboratory of Medical Sciences until Jul 2023, it is now run independently by a dedicated team of scientists and writers. The website aims to engage everyone, young and old, in the wonders of biology, and its influence on medicine. The ever-growing archive of more than 4000 research images documents over a decade of progress. Explore the collection and see what you discover. Images are kindly provided for inclusion on this website through the generosity of scientists across the globe.

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