Medical Research Council - London Institute of Medical Sciences

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Zombie Flies
31 January 2018

Zombie Flies

It sounds like the plot of a horror movie: a mind-controlling parasite that turns its victims into zombies and manipulates them to do its bidding. But this terrifying scenario actually happens in real life. The parasite is a fungus known as Entomophthora muscae and the hapless victims are fruit flies – often used as laboratory models for human disease. The fungus grows inside a fly’s body, feeding on its organs and fat. After a few days the parasite takes hold of the insect’s brain and starts controlling its movements. As the sun sets, the fly staggers towards the nearest high point, sticking its wings up in a characteristic ‘death pose’ (left panels). Over the next few hours (centre), the fungus begins to sprout from the dead insect’s belly in the form of small white spores. By morning (right) the spores are dripping from the lifeless wings, infecting any unlucky flies nearby.

Written by Kat Arney

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BPoD stands for Biomedical Picture of the Day. Managed by the MRC London Institute of Medical Sciences the website aims to engage everyone, young and old, in the wonders of biomedicine. Images are kindly provided for inclusion on this website through the generosity of scientists across the globe.

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