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Cabbages for Colons

Chemical produced during the digestion of brassicas (kale, cabbage etc.) may be effective at preventing colon cancer

05 September 2018

Cabbages for Colons

Most people understand the importance of eating their greens. But, in case you're someone that still balks at broccoli and sidesteps sprouts, research provides yet another incentive to add something green to your plate. According to experiments examining mouse colons (one pictured), a chemical produced during the digestion of kale, cabbage and other members of the Brassica genus – indole-3-carbinol– may be effective at both reducing colon inflammation and preventing colon cancer. When a strain of mouse normally prone to gut inflammation and cancer was given a diet rich in indole-3-carbinol, the animals’ colons were protected against inflammation and tumours. Furthermore, if such mice fed a normal diet began developing colon cancer, switching them to the indole-3-carbinol diet, reduced the number and malignancy of tumours that grew. Whether the results will hold true in humans is not known, but regardless it wouldn’t hurt to eat an extra sprout or two.

Written by Ruth Williams

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BPoD stands for Biomedical Picture of the Day. Managed by the MRC Laboratory of Medical Sciences until Jul 2023, it is now run independently by a dedicated team of scientists and writers. The website aims to engage everyone, young and old, in the wonders of biology, and its influence on medicine. The ever-growing archive of more than 4000 research images documents over a decade of progress. Explore the collection and see what you discover. Images are kindly provided for inclusion on this website through the generosity of scientists across the globe.

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