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Black Box

Uncovering details of primate early embryonic development

10 December 2019

Black Box

Over the past century, developmental biologists have learned a huge amount about the journey from a single cell to a fully-formed animal by studying model organisms such as frogs, fruit flies, worms and mice. Much less is known about the secrets of early development in our own species, or even in our closest primate relatives. Until recently it was only possible to study the first two weeks of human or primate development in the lab, as embryos can't survive any longer without being implanted into the womb. This means that scientists have missed out on studying the more complex processes of early development that happen after this point. Now a team of researchers have managed to extend this deadline even further, growing macaque embryos for up to twenty days in the lab (shown here with differentiating cells stained different colours), opening the ‘black box’ of early development and revealing intricate processes of life for the very first time.

Written by Kat Arney

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BPoD stands for Biomedical Picture of the Day. Managed by the MRC Laboratory of Medical Sciences until Jul 2023, it is now run independently by a dedicated team of scientists and writers. The website aims to engage everyone, young and old, in the wonders of biology, and its influence on medicine. The ever-growing archive of more than 4000 research images documents over a decade of progress. Explore the collection and see what you discover. Images are kindly provided for inclusion on this website through the generosity of scientists across the globe.

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