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Researching with Rotifers

Rotifers are providing insight into transgenerational epigenetics - inherited chemical modifications of genes

01 May 2019

Researching with Rotifers

We inherit our genes from mum and dad, and over time these DNA blueprints help us develop family similarities. Yet we also receive some of our parents’ epigenetics, chemicals that surround the genes controlling how they are used. Epigenetics are often affected by lifestyle and health, and in this way a mother’s age can directly affect their offspring. In humans, as in rotifers (like this one), elderly mothers often give birth to children who live shorter lives. But recent experiments suggest rotifers with older mothers react much more positively to caloric restriction – a healthy boost caused by a change in diet. As we share many genes in common with rotifers, with careful study this may mean choice of diet, medication or lifestyle might affect human children from young mothers or older mothers differently, and contribute to personalised medicine in the future.

Written by John Ankers

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BPoD stands for Biomedical Picture of the Day. Managed by the MRC Laboratory of Medical Sciences until Jul 2023, it is now run independently by a dedicated team of scientists and writers. The website aims to engage everyone, young and old, in the wonders of biology, and its influence on medicine. The ever-growing archive of more than 4000 research images documents over a decade of progress. Explore the collection and see what you discover. Images are kindly provided for inclusion on this website through the generosity of scientists across the globe.

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