Medical Research Council - London Institute of Medical Sciences

Now in our 9th year of bringing you beautiful imagery from biomedical science every day

Stressful Parenting

Reduced activity of two genes in the ovary associated with age-related infertility

01 June 2020

Stressful Parenting

As society evolves and our lifestyles shift, more and more people are choosing to have children later in life. Our bodies don’t always bend to our will, however, and a growing number of women are experiencing issues with infertility, stemming in part from the age-related decline of the ovaries. To better understand, and ultimately counter, this problem, researchers closely examined how the ovaries of primates (one pictured, with key features highlighted such as muscle filaments, green, muscle proteins, red, and DNA, blue) change as they age. They discovered that oxidative stress, a process that damages cells, plays an important role in ovarian ageing, and that genes typically involved in fighting it become less active with age. Comparing old and young monkey ovaries, and then data from healthy women, the researchers identified two key genes that slow with age, pointing to a promising potential target for the diagnosis and treatment of age-related infertility.

Written by Anthony Lewis

Search The Archive

Submit An Image

What is BPoD?

BPoD stands for Biomedical Picture of the Day. Managed by the MRC London Institute of Medical Sciences the website aims to engage everyone, young and old, in the wonders of biomedicine. Images are kindly provided for inclusion on this website through the generosity of scientists across the globe.

Read More

BPoD is also available in Catalan at www.bpod.cat with translations by the University of Valencia.