Medical Research Council - London Institute of Medical Sciences

Now in our 9th year of bringing you beautiful imagery from biomedical science every day

See Me Now

New approach allows individual gene-edited cells to be followed during development

13 September 2020

See Me Now

Precision gene editing techniques such as CRISPR have revolutionised biomedical research over the past few years. Scientists are now able to add, remove or alter specific genes – or even specific ‘letters’ of the genetic code – in ever more sophisticated ways in order to understand how genes work in healthy cells or organisms and what happens when they go wrong in disease. Two of the greatest challenges in the field are accuracy and efficiency, ensuring that only the right changes are made and that as many cells as possible are modified. These images of zebrafish embryos reveal the cells that have been altered using a new, highly specific gene editing tool, enabling researchers to follow distinct cell types during development. It's not just zebrafish – the new technique also works in pig and human cells, suggesting it could be used much more widely for genetic engineering and gene therapy in the future.

Written by Kat Arney

Search The Archive

Submit An Image

What is BPoD?

BPoD stands for Biomedical Picture of the Day. Managed by the MRC London Institute of Medical Sciences the website aims to engage everyone, young and old, in the wonders of biomedicine. Images are kindly provided for inclusion on this website through the generosity of scientists across the globe.

Read More

BPoD is also available in Catalan at www.bpod.cat with translations by the University of Valencia.