DYRK2 gene is vital for formation of normal cilia – hair-like projections on specialised cells – in mammals
They look like little hairs. Their name even means eyelashes in Latin. But you won’t spot cilia with your naked eye. These microscopic projections are found on certain specialised cells and have a host of important functions, from moving fluids and sensing signals, to helping embryos develop correctly. Now researchers probe how cilia themselves develop, focusing specifically on DYRK2, a gene already implicated in embryo development in roundworms. Deleting this gene in mice interfered with the transport of signalling proteins vital for proper embryo development. Notably, the absence of
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