Medical Research Council - London Institute of Medical Sciences

Now in our 12th year of bringing you beautiful imagery from biomedical science every day

Community Spirit

Bacterial strains growing in a 3D colony can co-operate and become genetically diverse by sharing secreted factors

14 June 2021

Community Spirit

When scientists study bacteria in the lab, they often grow them as flat colonies on plates of nutrient jelly or as single cells in a liquid broth. Out in the real world, things are very different. Bacteria in natural environments grow in three-dimensional communities known as biofilms, which can be made up of several different types of bugs. To discover more about how bacterial cells interact in biofilms, researchers have been seeing what happens when two types of bacteria are grown together in different conditions. One strain is normal (the middle row, and in red top row), and the other carries an alteration in the alrA gene (bottom row, in green top), which is involved in making the essential nutrient alanine. Cells without alrA die if grown in flat or liquid cultures but they will survive in biofilms by feeding on alanine produced by the normal cells around them, revealing how bacteria can co-operate together.

Written by Kat Arney

Search The Archive

Submit An Image

What is BPoD?

BPoD stands for Biomedical Picture of the Day. Managed by the MRC London Institute of Medical Sciences the website aims to engage everyone, young and old, in the wonders of biomedicine. Images are kindly provided for inclusion on this website through the generosity of scientists across the globe.

Read More

BPoD is also available in Catalan at www.bpod.cat with translations by the University of Valencia.